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Thus, the different volume regulation by SGLT2-I may limit the aberrant neurohumoral and RAAS stimulation that occurs in the setting of volume depletion ( Antihypertensive effects of SGLT2-i, which have been reported in clinical trials, are presumably due to their natriuretic effect
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Despite emerging competition from biosimilars approved in 2024, Eylea maintained its market leadership, aided by strategic inventory management and the therapeutic advantages of its new formulation
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